Can you take Keflex and Macrobid together. I have a resistant ecoli infection. It has been treated for a month and I am still in a lot of pain. Painkillers you can buy without a prescription, such as paracetamol and ibuprofen, are safe to take with nitrofurantoin. Speak to your doctor if these don't help with the headaches or the headaches are severe. Compare Cephalexin vs. Nitrofurantoin, which is better for uses like: UTI, Bladder Infection and Kidney Infection. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Cephalexin 2.9/5 over Nitrofurantoin 2.6/5 in overall satisfaction. As stated earlier although you can take Keflex and Macrobid together it is always better to be safe and check with a medical expert. They may also be able to suggest any other medication that could be more beneficial to you. Summary. Drug interactions are reported among people who take Cephalexin and Macrobid together. This study is created by eHealthMe based on reports of 152 people who take Cephalexin and Macrobid from FDA, and is updated regularly. Summary. Drug interactions are reported among people who take Cephalexin and Nitrofurantoin together. This study is created by eHealthMe based on reports of 163 people who take Cephalexin and Nitrofurantoin from FDA, and is updated regularly. If you're asking whether there are any contraindications in taking both together--adverse reactions or one of them decreasing the effect of the other--no, no problem here. It's OK to take them both together. Compare Cephalexin vs. trimethoprim, which is better for uses like: Infection, UTI and Bacterial Infection. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Cephalexin 2.9/5 over trimethoprim 2.3/5 in overall satisfaction. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Turck on can you take nitrofurantoin and doxycycline hyclate together: Sometimes both are used together to treat difficult cases of c difficil. When the doctor laughs at the patient, which cephalexin uses strep throat Cephalexin 500mg acne reviews , can i take cephalexin and nitrofurantoin together USD $39.95 Download Version.